产品名称
ZNF658 Rabbit Polyclonal Antibody
蛋白名称
Zinc finger protein 658
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26149
Human Swissprot No.
Q5TYW1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5TYW1
特异性
This antibody detects endogenous levels of ZNF658 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply.
