产品名称
WIPF2 Rabbit Polyclonal Antibody
基因名称
WIPF2 WICH WIRE PP10631
蛋白名称
WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=147179
Human Swissprot No.
Q8TF74
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TF74
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68524
Mouse Swissprot No.
Q6PEV3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PEV3/entry
特异性
This antibody detects endogenous levels of WIPF2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed mainly in brain, colon, lung and stomach (at protein level). Ubiquitously expressed, with high expression in brain, kidney, lung, and placenta.
细胞定位
Cytoplasm, cytoskeleton . Localized to stress fibers and bundles of actin filaments.
功能
Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.
