产品名称
SSF1 Rabbit Polyclonal Antibody
蛋白名称
Suppressor of SWI4 1 homolog (Ssf-1) (Brix domain-containing protein 3) (Peter Pan homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NQ55
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQ55/entry
Mouse Swissprot No.
Q91YU8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91YU8
免疫原
Synthesized peptide derived from part region of human protein
特异性
SSF1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. [provided by RefSeq, Nov 2010],
细胞定位
Nucleus, nucleolus .
功能
function:May have a role in cell growth.,miscellaneous:A putative trans-splicing which involves PPAN and P2RY11 gene regions produces a fusion protein.,similarity:Contains 1 Brix domain.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
