产品名称
TSEPA Rabbit Polyclonal Antibody
基因名称
THEMIS C6orf190 C6orf207
蛋白名称
Protein THEMIS (Thymocyte-expressed molecule involved in selection)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=387357
Human Swissprot No.
Q8N1K5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8N1K5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=210757
Mouse Swissprot No.
Q8BGW0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BGW0/entry
特异性
This antibody detects endogenous levels of TSEPA at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus .
功能
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
