产品名称
CIP2A Rabbit Polyclonal Antibody
蛋白名称
Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57650
Human Swissprot No.
Q8TCG1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TCG1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=224171
Mouse Swissprot No.
Q8BWY9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BWY9/entry
特异性
This antibody detects endogenous levels of CIP2A at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed at low levels in most of the tissues. Overexpressed in head-and-neck squamous cell carcinomas (HNSCC). Present in liver cancer cells (at protein level).
细胞定位
Membrane ; Single-pass membrane protein . Cytoplasm . Slightly concentrates in the perinuclear region (PubMed:12118381). .
功能
Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.
