产品名称
FAM120A Rabbit Polyclonal Antibody
基因名称
FAM120A C9orf10 KIAA0183 OSSA
蛋白名称
Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23196
Human Swissprot No.
Q9NZB2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NZB2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=218236
Mouse Swissprot No.
Q6A0A9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6A0A9/entry
特异性
This antibody detects endogenous levels of FAM120A at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Translocates to plasma membrane upon ultraviolet exposure.
功能
May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
