产品名称
STXBP4 Rabbit Polyclonal Antibody
蛋白名称
Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=252983
Human Swissprot No.
Q6ZWJ1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6ZWJ1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20913
Mouse Swissprot No.
Q9WV89
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WV89/entry
特异性
This antibody detects endogenous levels of STXBP4 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity).
