产品名称
SH3D19 Rabbit Polyclonal Antibody
蛋白名称
SH3 domain-containing protein 19 (ADAM-binding protein Eve-1) (EEN-binding protein) (EBP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=152503
Human Swissprot No.
Q5HYK7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5HYK7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27059
Mouse Swissprot No.
Q91X43
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91X43/entry
特异性
This antibody detects endogenous levels of SH3D19 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed with highest levels in heart, skeletal muscle, kidney, liver, placenta, small intestine and lung. Expressed at low levels in colon, thymus, spleen and leukocytes.
细胞定位
Cytoplasm . Nucleus . Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein.
功能
May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.
