产品名称
ENOX1 Rabbit Polyclonal Antibody
蛋白名称
Ecto-NOX disulfide-thiol exchanger 1 (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55068
Human Swissprot No.
Q8TC92
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TC92
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=239188
Mouse Swissprot No.
Q8BHR2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BHR2/entry
特异性
This antibody detects endogenous levels of ENOX1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells.
细胞定位
Cell membrane . Secreted, extracellular space . Extracellular and plasma membrane-associated.
功能
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock.
