产品名称
EFTUD1 Rabbit Polyclonal Antibody
蛋白名称
Elongation factor Tu GTP-binding domain-containing protein 1 (Elongation factor-like 1) (Protein FAM42A)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79631
Human Swissprot No.
Q7Z2Z2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q7Z2Z2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=101592
Mouse Swissprot No.
Q8C0D5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8C0D5/entry
特异性
This antibody detects endogenous levels of EFTUD1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed at low levels in brain. Expression is highly increased in glioma tissues.
功能
Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
