产品名称
CCDC94 Rabbit Polyclonal Antibody
蛋白名称
Coiled-coil domain-containing protein 94
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55702
Human Swissprot No.
Q9BW85
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BW85
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72886
Mouse Swissprot No.
Q9D6J3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D6J3/entry
特异性
This antibody detects endogenous levels of CCDC94 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA . Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates (By similarity). May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex .
