产品名称
DCXR Rabbit Polyclonal Antibody
蛋白名称
L-xylulose reductase (XR) (EC 1.1.1.10) (Carbonyl reductase II) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Sperm surface protein P34H)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51181
Human Swissprot No.
Q7Z4W1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q7Z4W1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67880
Mouse Swissprot No.
Q91X52
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91X52/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=171408
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q920P0/entry
特异性
This antibody detects endogenous levels of DCXR at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
细胞定位
Membrane ; Peripheral membrane protein . Probably recruited to membranes via an interaction with phosphatidylinositol. .
功能
Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
