产品名称
GLE1 Rabbit Polyclonal Antibody
蛋白名称
Nucleoporin GLE1 (hGLE1) (GLE1-like protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2733
Human Swissprot No.
Q53GS7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q53GS7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74412
Mouse Swissprot No.
Q8R322
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R322/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362098
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4KLN4/entry
特异性
This antibody detects endogenous levels of GLE1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm (PubMed:12668658). Shuttling is essential for its mRNA export function (PubMed:12668658). .; [Isoform 1]: Cytoplasm . Nucleus, nuclear pore complex . Shuttles between the nucleus and the cytoplasm (PubMed:12668658). In the nucleus, isoform 1 localizes to the nuclear pore complex and nuclear envelope (PubMed:12668658). Shuttling is essential for its mRNA export function (PubMed:12668658). .
功能
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
