产品名称
SREK1 Rabbit Polyclonal Antibody
蛋白名称
Splicing regulatory glutamine/lysine-rich protein 1 (Serine/arginine-rich-splicing regulatory protein 86) (SRrp86) (Splicing factor, arginine/serine-rich 12) (Splicing regulatory protein 508) (SRrp508)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8WXA9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WXA9/entry
Mouse Swissprot No.
Q8BZX4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BZX4
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9JKL7
免疫原
Synthesized peptide derived from part region of human protein
特异性
SREK1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
组织表达
Brain,Lung,Lymph node,Mammary gland,Pancrea
功能
function:Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Homodimer. Binds SFRS1, SFRS2, SFRS3 and SFRS6. Interacts with the spliceosome (By similarity). Interacts with P18SRP.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
