产品名称
VPS37B Rabbit Polyclonal Antibody
蛋白名称
Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79720
Human Swissprot No.
Q9H9H4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H9H4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=330192
Mouse Swissprot No.
Q8R0J7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R0J7/entry
特异性
This antibody detects endogenous levels of VPS37B at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Expressed in macrophages and lymphocytes.
细胞定位
Late endosome membrane ; Peripheral membrane protein . Recruited to the endosomal membrane in a VPS4A-dependent fashion.
功能
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.