产品名称
VPS13C Rabbit Polyclonal Antibody
蛋白名称
Vacuolar protein sorting-associated protein 13C
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54832
Human Swissprot No.
Q709C8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q709C8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=320528
Mouse Swissprot No.
Q8BX70
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BX70/entry
特异性
This antibody detects endogenous levels of VPS13C at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Mitochondrion outer membrane . Lipid droplet . Endoplasmic reticulum membrane . Lysosome membrane . Late endosome membrane . May localize to endoplasmic reticulum-endolysosome contact sites. .
功能
Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential . Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization .