BD-PN1362

SPF45 Rabbit Polyclonal Antibody

常规抗体

RBM17 SPF45

Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

84991

Q96I25

https://www.uniprot.org/uniprotkb/Q96I25/entry

Q8JZX4

http://www.uniprot.org/uniprot/Q8JZX4

Synthesized peptide derived from part region of human protein

SPF45 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

44kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009],

Epithelium,Eye,Liver,Testis,Uterus,

Nucleus .

Spliceosome;

function:Splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia.,similarity:Contains 1 G-patch domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds SXL. Associates with the spliceosome.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.