产品名称
TRIM36 Rabbit Polyclonal Antibody
基因名称
TRIM36 RBCC728 RNF98
蛋白名称
E3 ubiquitin-protein ligase TRIM36 (EC 6.3.2.-) (RING finger protein 98) (Tripartite motif-containing protein 36) (Zinc-binding protein Rbcc728)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55521
Human Swissprot No.
Q9NQ86
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NQ86
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=28105
Mouse Swissprot No.
Q80WG7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80WG7/entry
特异性
This antibody detects endogenous levels of TRIM36 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in testis, prostate and brain (PubMed:15145053). Weakly expressed in kidney, lung and heart (PubMed:15145053). Expressed in fetal tissues (PubMed:28087737).
细胞定位
Cytoplasm . Cytoplasmic vesicle, secretory vesicle, acrosome . Cytoplasm, cytoskeleton . Found in the acrosomal region of elongated spermatids and mature sperm. .
功能
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation . May play a role in the acrosome reaction and fertilization.
