产品名称
SUMF1 Rabbit Polyclonal Antibody
基因名称
SUMF1 FGE PSEC0152 UNQ3037/PRO9852
蛋白名称
Sulfatase-modifying factor 1 (EC 1.8.99.-) (C-alpha-formylglycine-generating enzyme 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=285362
Human Swissprot No.
Q8NBK3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8NBK3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58911
Mouse Swissprot No.
Q8R0F3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R0F3/entry
特异性
This antibody detects endogenous levels of SUMF1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitous. Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes, lung, placenta, small intestine, skeletal muscle and heart.
细胞定位
Endoplasmic reticulum lumen .
功能
Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent . 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile . Known substrates include GALNS, ARSA, STS and ARSE .
