产品名称
SLC22A14 Rabbit Polyclonal Antibody
蛋白名称
Solute carrier family 22 member 14 (Organic cation transporter-like 4) (ORCTL-4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9389
Human Swissprot No.
Q9Y267
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y267
特异性
This antibody detects endogenous levels of SLC22A14 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein . Cell projection, cilium, flagellum membrane ; Multi-pass membrane protein . Localizes to the principle piece of the sperm tail. .
功能
Riboflavin transporter localized at the inner mitochondrial membrane of the spermatozoa midpiece, which is required for male fertility (By similarity). SLC22A14-mediated riboflavin transport is essential for spermatozoa energy generation and motility: riboflavin is the precursor of FMN and FAD, which are coenzymes of many enzymes in the TCA cycle (the citric acid cycle) in mitochondria (By similarity). Required for sperm motility and normal sperm flagellar structure (By similarity).