产品名称
SELENBP1 Rabbit Polyclonal Antibody
蛋白名称
Selenium-binding protein 1 (56 kDa selenium-binding protein) (SBP56) (SP56)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8991
Human Swissprot No.
Q13228
Human Swissprot Link
https://www.uniprot.org/uniprot/Q13228
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20341
Mouse Swissprot No.
P17563
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P17563/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140927
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VIF7/entry
特异性
This antibody detects endogenous levels of SELENBP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.
细胞定位
Nucleus . Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . May associate with Golgi membrane (By similarity). May associate with the membrane of autophagosomes (By similarity). .
功能
Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria . Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity).
