BD-PN1370

SOAT1 Rabbit Polyclonal Antibody

常规抗体

SOAT1 ACACT ACACT1 ACAT ACAT1 SOAT STAT

Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1)

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

6646

P35610

https://www.uniprot.org/uniprotkb/P35610/entry

Q61263

http://www.uniprot.org/uniprot/Q61263

O70536

http://www.uniprot.org/uniprot/O54941O70536

Synthesized peptide derived from part region of human protein

SOAT1 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000

60kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011],

Macrophage,Placenta,

Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Steroid biosynthesis;

catalytic activity:Acyl-CoA + cholesterol = CoA + cholesterol ester.,disease:Accumulation of insoluble cholesterol esters in macrophages and smooth muscle is a characteristic feature of early lesions of atherosclerotic plaque.,function:Catalyzes the formation of fatty acid-cholesterol esters. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.,induction:Highly activated by the presence of cholesterol.,similarity:Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.,subunit:May form homo- or heterodimers.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.