产品名称
OMCG1 Rabbit Polyclonal Antibody
蛋白名称
Zinc finger protein 830 (Coiled-coil domain-containing protein 16)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=91603
Human Swissprot No.
Q96NB3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96NB3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66983
Mouse Swissprot No.
Q8R1N0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R1N0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=497967
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q3MHS2/entry
特异性
This antibody detects endogenous levels of OMCG1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Chromosome . Nucleus speckle . Excluded from nucleolus. .
功能
May play a role in pre-mRNA splicing as component of the spliceosome . Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (By similarity).
