产品名称
MTBP Rabbit Polyclonal Antibody
蛋白名称
Mdm2-binding protein (hMTBP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27085
Human Swissprot No.
Q96DY7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96DY7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=105837
Mouse Swissprot No.
Q8BJS8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BJS8/entry
特异性
This antibody detects endogenous levels of MTBP at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
