产品名称
MSL3 Rabbit Polyclonal Antibody
蛋白名称
Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10943
Human Swissprot No.
Q8N5Y2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8N5Y2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17692
Mouse Swissprot No.
Q9WVG9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WVG9/entry
特异性
This antibody detects endogenous levels of MSL3 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.
功能
Has a role in chromatin remodeling and transcriptional regulation . Has a role in X inactivation . Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure . Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex .
