产品名称
ICMT Rabbit Polyclonal Antibody
蛋白名称
Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23463
Human Swissprot No.
O60725
Human Swissprot Link
https://www.uniprot.org/uniprot/O60725
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57295
Mouse Swissprot No.
Q9EQK7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9EQK7/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WVM4/entry
特异性
This antibody detects endogenous levels of ICMT at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
