产品名称
CCDC40 Rabbit Polyclonal Antibody
蛋白名称
Coiled-coil domain-containing protein 40
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55036
Human Swissprot No.
Q4G0X9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q4G0X9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=207607
Mouse Swissprot No.
Q8BI79
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BI79/entry
特异性
This antibody detects endogenous levels of CCDC40 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Cell projection, cilium . Localizes to cytoplasm and motile cilium. .
功能
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella . Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 .
