产品名称
C1orf187 Rabbit Polyclonal Antibody
基因名称
DRAXIN C1orf187 PSEC0258 UNQ3119/PRO10268
蛋白名称
Draxin (Dorsal inhibitory axon guidance protein) (Dorsal repulsive axon guidance protein) (Neucrin)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=374946
Human Swissprot No.
Q8NBI3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8NBI3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70433
Mouse Swissprot No.
Q6PAL1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PAL1/entry
特异性
This antibody detects endogenous levels of C1orf187 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.