产品名称
ASPRV1 Rabbit Polyclonal Antibody
蛋白名称
Retroviral-like aspartic protease 1 (EC 3.4.23.-) (Skin-specific retroviral-like aspartic protease) (SASPase) (Skin aspartic protease) (TPA-inducible aspartic proteinase-like protein) (TAPS)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=151516
Human Swissprot No.
Q53RT3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q53RT3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67855
Mouse Swissprot No.
Q09PK2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q09PK2/entry
特异性
This antibody detects endogenous levels of ASPRV1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent from ulcerated regions. Expressed in differentiated areas of squamous cell carcinomas but not in undifferentiated tumors.
细胞定位
Membrane ; Single-pass membrane protein .
功能
Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization.
