产品名称
AF-6 Rabbit Polyclonal Antibody
蛋白名称
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4301
Human Swissprot No.
P55196
Human Swissprot Link
https://www.uniprot.org/uniprot/P55196
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17356
Mouse Swissprot No.
Q9QZQ1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QZQ1/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26955
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O35889/entry
特异性
This antibody detects endogenous levels of AF-6 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell junction, adherens junction . Not found at cell-matrix AJs. .
功能
Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs) (By similarity). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton . May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions .
