产品名称
EIF4E2 Rabbit Polyclonal Antibody
蛋白名称
Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (mRNA cap-binding protein type 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9470
Human Swissprot No.
O60573
Human Swissprot Link
https://www.uniprot.org/uniprot/O60573
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26987
Mouse Swissprot No.
Q8BMB3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BMB3/entry
特异性
This antibody detects endogenous levels of EIF4E2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Cytoplasm, P-body .
功能
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation . Acts as a repressor of translation initiation . In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity). In P-bodies, component of a complex that promotes miRNA-mediated translational repression .
