产品名称
PGCP Rabbit Polyclonal Antibody
蛋白名称
Carboxypeptidase Q (EC 3.4.17.-) (Lysosomal dipeptidase) (Plasma glutamate carboxypeptidase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10404
Human Swissprot No.
Q9Y646
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y646
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54381
Mouse Swissprot No.
Q9WVJ3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WVJ3/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58952
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IRK9/entry
特异性
This antibody detects endogenous levels of PGCP at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles, liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level).
细胞定位
Endoplasmic reticulum . Golgi apparatus . Lysosome . Secreted . Secretion is stimulated by TSH/thyroid-stimulating hormone, INS/insulin and SST/somatostatin. .
功能
Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.