产品名称
AKTIP Rabbit Polyclonal Antibody
蛋白名称
AKT-interacting protein (Ft1) (Fused toes protein homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64400
Human Swissprot No.
Q9H8T0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H8T0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14339
Mouse Swissprot No.
Q64362
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q64362/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=291906
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5FVH4/entry
特异性
This antibody detects endogenous levels of AKTIP at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein .
功能
Component of the FTS/Hook/FHIP complex (FHF complex) . The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell .
