产品名称
C3orf39 Rabbit Polyclonal Antibody
基因名称
GTDC2 AGO61 C3orf39 EOGTL
蛋白名称
Glycosyltransferase-like domain-containing protein 2 (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase-like)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84892
Human Swissprot No.
Q8NAT1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8NAT1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=215494
Mouse Swissprot No.
Q8BW41
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BW41/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=316091
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5NDF0/entry
特异性
This antibody detects endogenous levels of C3orf39 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in the brain, muscle, heart, and kidney in both fetus and adult. In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas.
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
功能
O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.
