产品名称
ARAP2 Rabbit Polyclonal Antibody
基因名称
ARAP2 CENTD1 KIAA0580
蛋白名称
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (Centaurin-delta-1) (Cnt-d1) (Protein PARX)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116984
Human Swissprot No.
Q8WZ64
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8WZ64
Mouse Swissprot No.
Q8BZ05
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BZ05/entry
特异性
This antibody detects endogenous levels of ARAP2 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes.
功能
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity).
