产品名称
JP45/JSRP1 Rabbit Polyclonal Antibody
蛋白名称
Junctional sarcoplasmic reticulum protein 1 (Junctional-face membrane protein of 45 kDa homolog) (JP-45)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=126306
Human Swissprot No.
Q96MG2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96MG2
Mouse Swissprot No.
Q3MI48
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3MI48/entry
特异性
This antibody detects endogenous levels of JP45/JSRP1 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Sarcoplasmic reticulum membrane . Endoplasmic reticulum membrane . Colocalizes with ryanodine receptors at the sarcoplasmic reticulum triad membranes. .
功能
Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity.
