产品名称
SMU1 Rabbit Polyclonal Antibody
蛋白名称
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55234
Human Swissprot No.
Q2TAY7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q2TAY7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74255
Mouse Swissprot No.
Q3UKJ7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UKJ7/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=117541
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q99M63/entry
特异性
This antibody detects endogenous levels of SMU1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus . Nucleus speckle . Colocalizes with SRSF1 in nuclear speckles. .
功能
Involved in pre-mRNA splicing as a component of the spliceosome . Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity). Required for normal accumulation of IK . Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). ; (Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
