产品名称
TWSG1 Rabbit Polyclonal Antibody
蛋白名称
Twisted gastrulation protein homolog 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57045
Human Swissprot No.
Q9GZX9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9GZX9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65960
Mouse Swissprot No.
Q9EP52
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9EP52/entry
特异性
This antibody detects endogenous levels of TWSG1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).
