产品名称
SL9A2 Rabbit Polyclonal Antibody
蛋白名称
Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UBY0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UBY0/entry
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P48763
免疫原
Synthesized peptide derived from part region of human protein
特异性
SL9A2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the sodium-hydrogen exchanger (NHE) protein family. These proteins are involved in sodium-ion transport by exchanging intracellular hydrogen ions to external sodium ions and help in the regulation of cell pH and volume. The encoded protein is localized to the apical membrane and is involved in apical absorption of sodium. [provided by RefSeq, Jun 2016],
组织表达
Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.
细胞定位
Membrane; Multi-pass membrane protein.
功能
caution:The number, localization and denomination of hydrophobic domains in the Na(+)/H(+) exchangers vary among authors.,function:Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.,PTM:Phosphorylated (Possible).,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,tissue specificity:Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
