产品名称
RNF170 Rabbit Polyclonal Antibody
蛋白名称
E3 ubiquitin-protein ligase RNF170 (EC 6.3.2.-) (Putative LAG1-interacting protein) (RING finger protein 170)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81790
Human Swissprot No.
Q96K19
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96K19
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=77733
Mouse Swissprot No.
Q8CBG9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CBG9/entry
特异性
This antibody detects endogenous levels of RNF170 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in the spinal chord.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.
