产品名称
LY6H Rabbit Polyclonal Antibody
蛋白名称
Lymphocyte antigen 6H (Ly-6H)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4062
Human Swissprot No.
O94772
Human Swissprot Link
https://www.uniprot.org/uniprot/O94772
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23934
Mouse Swissprot No.
Q9WUC3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WUC3/entry
特异性
This antibody detects endogenous levels of LY6H at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic cell line MOLT-3. Also found in lower levels in testis, pancreas, small intestine and colon.
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor .
功能
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.
