产品名称
GLRA2 Rabbit Polyclonal Antibody
蛋白名称
Glycine receptor subunit alpha-2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2742
Human Swissprot No.
P23416
Human Swissprot Link
https://www.uniprot.org/uniprot/P23416
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=237213
Mouse Swissprot No.
Q7TNC8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TNC8/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100910572
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P22771/entry
特异性
This antibody detects endogenous levels of GLRA2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell junction, synapse . Cell membrane ; Multi-pass membrane protein . Cell projection .
功能
Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine . Channel opening is also triggered by taurine and beta-alanine . Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents . Plays a role in cellular responses to ethanol .