产品名称
CCDC62 Rabbit Polyclonal Antibody
蛋白名称
Coiled-coil domain-containing protein 62 (Protein TSP-NY) (Protein aaa)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84660
Human Swissprot No.
Q6P9F0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6P9F0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=208908
Mouse Swissprot No.
E9PVD1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/E9PVD1/entry
特异性
This antibody detects endogenous levels of CCDC62 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in adult testis. Expressed in both prostate epithelial and stromal cells, with predominant expression in epithelial cells (at protein level) (PubMed:19126643). Not detected in prostate by RT-PCR (PubMed:19165854). Overexpressed in various cancers.
细胞定位
Cytoplasm . Nucleus . Mainly nuclear.
功能
Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR.
