产品名称
IKIP Rabbit Polyclonal Antibody
蛋白名称
Inhibitor of nuclear factor kappa-B kinase-interacting protein (I kappa-B kinase-interacting protein) (IKBKB-interacting protein) (IKK-interacting protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=121457
Human Swissprot No.
Q70UQ0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q70UQ0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67454
Mouse Swissprot No.
Q9DBZ1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9DBZ1/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=314730
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5EAJ6/entry
特异性
This antibody detects endogenous levels of IKIP at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle.
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein . Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization.
功能
Target of p53/TP53 with pro-apoptotic function.
