产品名称
CDX1 Rabbit Polyclonal Antibody
蛋白名称
Homeobox protein CDX-1 (Caudal-type homeobox protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1044
Human Swissprot No.
P47902
Human Swissprot Link
https://www.uniprot.org/uniprot/P47902
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12590
Mouse Swissprot No.
P18111
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P18111/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q05095/entry
特异性
This antibody detects endogenous levels of CDX1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Intestinal epithelium.
功能
Plays a role in transcriptional regulation . Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells . Binds to the PRKD1 promoter in colorectal cancer (CRC) cells . Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA .