产品名称
ANKRD16 Rabbit Polyclonal Antibody
蛋白名称
Ankyrin repeat domain-containing protein 16
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54522
Human Swissprot No.
Q6P6B7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6P6B7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=320816
Mouse Swissprot No.
A2AS55
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A2AS55/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=307102
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q499M5/entry
特异性
This antibody detects endogenous levels of ANKRD16 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus .
功能
Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides.