产品名称
EAPP Rabbit Polyclonal Antibody
基因名称
EAPP C14orf11 BM-036
蛋白名称
E2F-associated phosphoprotein (EAPP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55837
Human Swissprot No.
Q56P03
Human Swissprot Link
https://www.uniprot.org/uniprot/Q56P03
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66266
Mouse Swissprot No.
Q5BU09
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5BU09/entry
特异性
This antibody detects endogenous levels of EAPP at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts.
功能
May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression.