产品名称
SHKBP1 Rabbit Polyclonal Antibody
蛋白名称
SH3KBP1-binding protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=92799
Human Swissprot No.
Q8TBC3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TBC3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=192192
Mouse Swissprot No.
Q6P7W2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P7W2/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=292735
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P0C5J9/entry
特异性
This antibody detects endogenous levels of SHKBP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
