产品名称
TMTC1 Rabbit Polyclonal Antibody
蛋白名称
Transmembrane and TPR repeat-containing protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83857
Human Swissprot No.
Q8IUR5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8IUR5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=387314
Mouse Swissprot No.
Q3UV71
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UV71/entry
特异性
This antibody detects endogenous levels of TMTC1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Membrane ; Multi-pass membrane protein . Endoplasmic reticulum .
功能
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.