产品名称
SETD6 Rabbit Polyclonal Antibody
蛋白名称
N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79918
Human Swissprot No.
Q8TBK2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TBK2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66083
Mouse Swissprot No.
Q9CWY3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CWY3/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=291844
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D3ZSK5/entry
特异性
This antibody detects endogenous levels of SETD6 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity . Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) . Required for the maintenance of embryonic stem cell self-renewal (By similarity). Methylates PAK4.
